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详细介绍
DBCO-PEG-MAL,二苯基环辛炔PEG马来酰亚胺,(Dibenzocyclooctyne)PEG
结构式：
基本信息：
中文名：二苯基环辛炔PEG马来酰亚胺，二苯基环辛炔聚乙二醇马来酰亚胺
英文名：DBCO-PEG-MAL, Dibenzocyclooctyne-PEG-Maleimide
分子量：400、600、1K、2K、3.4K、4K、5K、10K
应用简介：
Maleimide PEG DBCO (dibenzocycolctyne) is DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aueous solution. DBCO PEG derivatives possess fast kinetics and stability in aueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Copper-free Click Reaction Procedures:
Prepare the azide-containing reagents in reaction buffer.
Add DBCO reagents to azide containing reagents. Add 1 mol euivalent of limiting reagent to 1.5~3.0 mol euivalents of abundance reagent.
Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4℃.
Purify conjugates either by dialysis or size-exclusion chromatograph.
物理性质：
状态：淡黄色到黄色固体，或者半固体，取决于分子量。
溶解性：溶于DMSO,DMF等溶剂。
保持条件：-20℃长期保存，避光，干燥。
注意事项：取用一定要干燥，避免频繁的溶解和冻干。
反应性：DBCO于含有N3基团的反应。MAL可以和SH。
DBCO（Dibenzocyclooctyne）PEGs其他产品:
DBCO-PEG-MAL,MW:2000 二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-MAL,MW:3400 二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-MAL,MW:5000 二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-MAL,MW:10000 二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-NH2,MW:2000 二苯基环辛炔PEG氨基
DBCO-PEG-NH2,MW:3400 二苯基环辛炔PEG氨基
DBCO-PEG-NH2,MW:5000 二苯基环辛炔PEG氨基
DBCO-PEG-NH2,MW:10000 二苯基环辛炔PEG氨基
mPEG-DBCO,MW:1000 甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:2000 甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:3400 甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:5000 甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:10000 甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:20000 甲氧基PEG二苯基环辛炔
DBCO-PEG-NHS,MW:2000 二苯基环辛炔PEG活性酯
DBCO-PEG-NHS,MW:3400 二苯基环辛炔PEG活性酯
DBCO-PEG-NHS,MW:5000 二苯基环辛炔PEG活性酯
DBCO-PEG-NHS,MW:10000二苯基环辛炔PEG活性酯
DBCO-PEG-Biotin,MW:2000 二苯基环辛炔PEG生物素
DBCO-PEG-Biotin,MW:3400 二苯基环辛炔PEG生物素
DBCO-PEG-Biotin,MW:5000 二苯基环辛炔PEG生物素
DBCO-PEG-Biotin,MW:10000 二苯基环辛炔PEG生物素
DBCO-PEG-COOH,MW:2000 二苯基环辛炔PEG羧酸
DBCO-PEG-COOH,MW:3400 二苯基环辛炔PEG羧酸
DBCO-PEG-COOH,MW:5000 二苯基环辛炔PEG羧酸
DBCO-PEG-COOH,MW:10000二苯基环辛炔PEG羧酸
DBCO-PEG-Folate,MW:2000 二苯基环辛炔PEG叶酸
DBCO-PEG-Folate,MW:3400 二苯基环辛炔PEG叶酸
DBCO-PEG-Folate,MW:5000 二苯基环辛炔PEG叶酸
DBCO-PEG-Cholesterol,MW:2000 二苯基环辛炔PEG胆固醇
DBCO-PEG-Cholesterol,MW:3400 二苯基环辛炔PEG胆固醇
DBCO-PEG-Cholesterol,MW:5000 二苯基环辛炔PEG胆固醇
DBCO-PEG-Glucose,MW:2000 二苯基环辛炔PEG葡萄糖
DBCO-PEG-Glucose,MW:5000 二苯基环辛炔PEG葡萄糖
DBCO-PEG-Silane,MW:2000 二苯基环辛炔PEG硅烷
DBCO-PEG-Silane,MW:3400 二苯基环辛炔PEG硅烷
DBCO-PEG-Silane,MW:5000 二苯基环辛炔PEG硅烷
DBCO-PEG-MAL,二苯基环辛炔PEG马来酰亚胺,(Dibenzocyclooctyne)PEG
| Structure | M.W. | Purity |
|---|---|---|
DBCO-acid & DBCO-PEG acid | ||
| DBCO-acid |  | 98% |
| DBCO-C6-acid |  | 96% |
| DBCO-PEG4-acid |  | 98% |
| DBCO-PEG5-acid |  | 95% |
| DBCO-PEG13-acid |  | 98% |
| DBCO-CONH-PEG4-acid |  | 95% |
DBCO-NHS ester | ||
| DBCO-NHS |  | 97% |
| DBCO-C6-NHS ester |  | 95% |
| DBCO-Sulfo-NHS ester |  | 97% |
DBCO-PEG-NHS ester | ||
| DBCO-PEG4-NHS ester |  | 96% |
| DBCO-PEG5-NHS ester |  | 95% |
| DBCO-PEG13-NHS ester |  | 90% |
| DBCO-CONH-PEG4-NHS ester |  | 97% |
| PC DBCO-PEG4-NHS ester |  | 95% |
DBCO-PEG-PFP ester | ||
| DBCO-PEG4-PFP ester |  | 95% |
DBCO-PEG-Alcohol | ||
| DBCO-PEG4-alcohol |  | 95% |
DBCO-amine & DBCO-PEG-amine | ||
| DBCO-amine |  | 96% |
| Sulfo DBCO-amine |  | 95% |
| DBCO-PEG4-amine |  | 98% |
| Sulfo DBCO-PEG4-amine |  | 95% |
DBCO-PEG-NH-Boc | ||
| DBCO-PEG4-NH-Boc |  | 97% |
BDP FL DBCO | ||
| BDP FL DBCO |  | 95% |
Fluorescein-DBCO | ||
| Fluorescein-DBCO |  | 95% |
Carboxyrhodamine-PEG-DBCO | ||
| Carboxyrhodamine 110PEG4-DBCO |  | 95% |
Sulforhodamine-PEG-DBCO | ||
| Sulforhodamine-PEG4-DBCO |  | 95% |
TAMRA-PEG-DBCO | ||
| TAMRA-PEG4-DBCO |  | 95% |
DBCO-Biotin & DBCO-PEG-Biotin | ||
| DBCO-PEG4-biotin |  | 95% |
| DBCO-Sulfo-Link-biotin |  | 95% |
| DBCO-PEG4-Desthiobiotin |  | 95% |
DBCO-PEG-DBCO | ||
| DBCO-PEG4-DBCO |  | 95% |
| DBCO-PEG5-DBCO |  | 95% |
DBCO-Maleimide & DBCO-PEG-Maleimide | ||
| DBCO-Maleimide |  | 95% |
| Sulfo DBCO-Maleimide |  | 95% |
| DBCO-PEG4-Maleimide |  | 95% |
| Sulfo DBCO-PEG4-Maleimide |  | 90% |
TCO-PEG-DBCO | ||
| TCO-PEG12-DBCO |  | 95% |
Tetrazine-PEG-DBCO | ||
| Methyltetrazine-PEG12-DBCO |  | 95% |
| Methyltetrazine-DBCO |  | 95% |
DBCO-mPEG | ||
| DBCO-mPEG 5KDa |  | |
| DBCO-mPEG 10KDa |  | |
| DBCO-mPEG 20KDa |  | |
DBCO-PEG-MAL,二苯基环辛炔PEG马来酰亚胺,(Dibenzocyclooctyne)PEG
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