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详细介绍
杭州新乔生物科技有限公司可以提供一种用于肿瘤癌症细胞的光热治疗和光动力治疗的近红外荧光染料IR-825，该产品的吸收波长是810nm,发射波长是830nm,该产品的末端带有羧基COOH活性基团可以参与反应连接其他分子，这个产品的造价要低于ICG-COOH，可以广泛用于肿瘤的光热治疗。我公司制备的IR-825纯度95.4%，可以溶解在二氯甲烷、甲醇、DMF、DMSO里。
特别说明：该产品仅仅用于科学研究，不用于人体及药物开发
本公司销售各种荧光染料及活性荧光染料，产品质量稳定，纯度大于95%，可以提供COA和核磁、HPLC图谱报告，2周内如遇质量问题无条件退换货，产品产自西安瑞禧生物。
Certificate of Analysis
General properties:
Name：IR825
Molecular Weight：823.4 Dalton
Molecular Formula : C54H48CIN2O4
CAS.#：1558079-49-4
Lot.#： RM017172
Date of Analysis：2018.01.09
Recommended Retest date：2019.01.09
Stability： 12 months
Storage： -20°C in the dark
Items |
| Specification | Results |
Appearance |
| solid | solid |
1H NMR |
| Identical to the structure | Identical to the structure |
Foreign Material |
| None | None |
Purity by HPLC |
| ＞95% | 95.4% |
IR-825 is a near-infrared dye (NIR). IR-825, after encapsulated into nanoparticles may be useful for cancer photothermal and photodynamic therapy. IR-825 nanoparticles showed pH-dependent fluorescence emission and excellent near-infrared (NIR) irradiation of cancer cells targeted in vitro to provide cytotoxicity. IR-825 nanoparticles showed efficient tumor homing together with rapid renal excretion behaviors, as revealed by MR imaging and confirmed by biodistribution measurement. Notably, when irradiated with an 808 nm laser, tumors on mice with IR-825 nanoparticle injection are compley eliminated without recurrence within 60 days, demonstrating the high efficacy of photothermal therapy.
IR-825 CAS1558079-49-4 ，近红外荧光染料
IR-825 CAS1558079-49-4 ，近红外荧光染料
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