炔雌醇
中文名称: 炔雌醇
中文别名: 乙炔雌二醇
英文名称: Ethinylestradiol
EINECS号: 200-342-2
分子式: C20H24O2
分子量: 296.4034
57-63-6
密度: 1.21g/cm3
熔点: 182-183℃
沸点: 457.2°C at 760 mmHg
闪点: 211.2°C
蒸汽压: 3.74E-09mmHg at 25°C
物化性质:
熔点:142 - 146
水溶性:<0.1 g/100 mL at 21 C
产品用途:
属雌激素类药
为3-羟基-19-去甲-17α-孕甾-1,3,5(10)-三烯-20-炔-17-醇。
按干燥品计算,含C20H24O2应为97.0%~103.0%。
本品为白色或类白色的结晶性粉末;无臭
在水中不溶。本品的熔点(附录ⅥC)为180~186℃。
Product Name: Ethynyl estradiol
Synonyms: NOVESTROL;NEO-ESTRONE;ETHYNYLESTRADIOL;ETHINYL ESTRADIOL;LYNORAL;17ALPHA-ETHYNYL-DELTA1,3,5(10)-ESTRA-TRIENE-3,17BETA-DIOL;17ALPHA-ETHYNYLESTRADIOL;17ALPHA-ETHINYLESTRADIOL
CAS: 57-63-6
MF: C20H24O2
MW: 296.4
EINECS: 200-342-2
Ethynyl estradiol Chemical Properties
Melting point 182-183 °C(lit.)
refractive index -30 ° (C=0.4, Pyridine)
storage temp. -20°C Freezer
solubility ethanol: 50 mg/mL, clear, slightly yellow
Ethynyl estradiol Usage And Synthesis
Chemical Properties Off-White to Light-Yellow Crystalline Powder
Usage A metabolite of 17a-Ethynylestradiol
Usage A synthetic steroid with high oral estrogenic potency
Usage estrogen, plus progestogen as oral contraceptive
General Description Fine white to creamy white powder. A synthetic steroid. Used in combination with progestogen as an oral contraceptive.
Air & Water Reactions Air and light sensitive . Insoluble in water.
Reactivity Profile Ethynyl estradiol may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to generate gaseous hydrogen.