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Recombinant Murine EGF 货号:315-09 细胞因子

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更新时间:2016-01-14 20:29:42浏览次数:6763次

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Recombinant Murine EGF 货号:315-09 细胞因子
细胞因子(cytokine,CK)是一类能在细胞间传递信息、具有免疫调节和效应功能的蛋白质或小分子多肽。
作用特点:多效性、重叠性、协同性、拮抗性和双重性。

详细介绍

Recombinant Murine EGF 货号:315-09 细胞因子 

细胞因子受体的结构和分类:根据细胞因子受体cDNA序列以及受体胞膜外区氨基酸序列的同源性和结构征,可将细胞因子受体主要分为四种类型:免疫球蛋白超家族(IGSF)、造血细胞因子受体超家族、神经生长因子受体超家族和趋化因子受体。

 

Catalog Number:
315-09
Synonyms:
Epidermal Growth Factor, Urogastrone, URG
Description:
Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant murine EGF is a 6.0 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide-bonds.
AA Sequence:
NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 was determined by a cell proliferation assay using BALB/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
 
 
 
 
Cross Reactivity:
Human, Mouse, Rat
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular Cancer Cancer
Cell Culture Cell Culture Inflammation Inflammation
Neurobiology Neurobiology Proliferation Proliferation
Stem Cells & Differentiation Stem Cells & Differentiation Wound Healing Wound Healing
 
 
Country of Origin:
USA


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