Tetrazines demonstrate exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In addition, inverse-Electron-Demand Diels-Alder reaction of tetrazines trans-cyclooctenea forms a stable covalent bond and does not require Cu-catalyst or elevated temperatures. In applications such as in vivo cancer imaging or pre‐targeted cell labeling studies where rapid reaction kinetics are desired, a faster hydrogen substituted Cy®3 Tetrazine probe would be a probe of choice.

       
 
Cy®3 is a bright, water-soluble, and pH insensitive orange-fluorescent dye that can be excited using the 532 nm or 555 nm laser line and visualized with TRITC (tetramethylrhodamine) filter sets. Cy3 conjugates give less background than TAMRA and most other monly used fluorescent dyes.        
 

供应商：西安凯新生物科技有限公司

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General properties:

Appearance:	dark red solid
Mass spec M+ increment:	611.4
Molecular weight:	727.64
Molecular formula:	C40H46N7BF4O
Solubility:	good in DCM, DMSO, DMF
Storage conditions:	Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

Excitation maximum, nm:	555
ε, L⋅mol−1⋅cm−1:	150000
Emission maximum, nm:	570
Fluorescence quantum yield:	0.31
CF260:	0.04
CF280:	0.09

其他荧光产品：
5-TAMRA Azide           1006592-61-5
3-Azidopropionic Acid   18523-47-2
3-Azidopropionic Acid Sulfo-NHS Ester  
3-Ethynyl perylene      132196-66-8
4-(6-phenyl-1,2,4,5-tetrazin -3-yl)-Benzenamine 1414370-48-1
4MMDPA  
4MTDA  
4PhSO2-PyMTA  
4vinylDPA  
4vinylPyMTA  
5(6)-Carboxyfluorescein N-succinimidyl ester 117548-22-8
5(6)-TAMRA ethylenediamine  
5-Carboxyfluorescein diacetate     79955-27-4
5-TAMRA Picolyl Azide  
5-vinyl-2'-deoxyuridine            55520-67-7
6-[1,4-dihydro-6-(2-pyridinyl)-1,2,4,5-tetrazin-3-yl]- 3-pyridinamine 1055983-13-5
6-[6-(2-pyridinyl)-1,2,4,5-tetrazin-3-yl]- 3-pyridinamine 1055983-02-2
6-Azidohexanoic Acid               79598-53-1
6-Azidohexanoic Acid Sulfo-NHS Ester  
6-Carboxyfluorescein succinimidyl ester 92557-81-8
6-TAMRA Azide  
Alkyne hydrazide  
Alkyne maleimide  
Alkyne NHS ester (hexynoic acid NHS ester) 906564-59-8
alkyneDTTAC           1585198-91-9
Alkyne-PEG4-Acid      1245823-51-1
Alkyne-PEG4-Amine     1013921-36-2
Alkyne-PEG4-Maleimide 1609651-90-2
Alkyne-PEG4-NHS Ester 1393330-40-9
AmdU (5-azidomethyl-2'-deoxyuridine)  
Amino-PEG2-t-butyl ester 756525-95-8
Amino-PEG3-t-butyl ester 252881-74-6
Amino-PEG4-amine      68960-97-4
Amino-PEG4-t-butyl ester 581065-95-4
Amino-PEG5-CH2CO2H    141282-35-1
Amino-PEG6-acid       905954-28-1
Amino-PEG6-alcohol    39160-70-8
Azidobutyric acid NHS ester  
Azido-PEG23 amine     749244-38-0
Azido-PEG3-acid       1056024-94-2
Azido-PEG3-Amine      134179-38-7
Azido-PEG3-Maleimide  1858264-36-4
Azido-PEG4-Acid       1257063-35-6
Azido-PEG4-alcohol    770-67-4
Azido-PEG4-azide      182760-73-2
Azido-PEG4-NHS ester  944251-24-5
Azido-PEG8-acid       1214319-92-2
Azido-Propylamine     88192-19-2
Biotin alkyne  
Biotin azide          908007-17-0
Biotin Picolyl Azide  
Biotin-PEG3-Azide     875770-34-6
Biotin-PEG3-Bis-sulfone  
Biotin-PEG4-Alkyne    1262681-31-1
Biotin-PEG4-azido  
Biotin-PEG4-Methyltetrazine  
Biotin-PEG4-NHS ester 459426-22-3
Bis-maleimides-amine TFA salt 252335-97-0
Bis-PEG5-acid         439114-13-3
Bis-sulfone-PEG3-Azide  
Bis-sulfone-PEG4-DBCO  
Bis-sulfone-PEG4-Tetrazine  
Carbamic acid, N-(2-hydroxyethyl)-, (2-methyl-2-cyclopropen-1-yl)methyl ester 1402265-33-1
Carboxyrhodamine 110 Alkyne  
Carboxyrhodamine 110 Azide  
Carboxyrhodamine 110 DBCO  
Cy3 Alkyne  
Cy3 Azide  
Cy3 DBCO 1782950-79-1
Cy3 Methyltetrazine   1676067-48-3
Cy3 Picolyl Azide  
Cy3 Tetrazine  
Cy5 Alkyne  
Cy5 Azide             1782950-80-4
Cy5 DBCO              15642-24-3
Cy5 Methyltetrazine  
Cy5 Picolyl Azide  
Cy5 Tetrazine  
Cy5.5 Alkyne  
Cy5.5 Azide  
Cy5.5 DBCO  
Cy5.5 Picolyl Azide  
Cy5-Biotin-Azide  
Cy5-TCO  
Cy7 Alkyne  
Cy7 Azide  
Cy7 DBCO  
Cy7 Methyltetrazine  
Cyanine3 alkyne  
Cyanine3 amine  
Cyanine3 azide  
Cyanine3 carboxylic acid 1144107-76-5
Cyanine3 DBCO  
Cyanine3 hydrazide  
3,6-Bis(2-Pyridyl)- 1,2,4,5-Tetrazine 1671-87-0
Amino-PEG3-amine      929-75-9
5-TAMRA-Tz  
Amino-PEG4-acid       663921-15-1
Azidoacetic Acid      18523-48-3
Azidoacetic Acid NHS Ester 824426-32-6
Cyanine3 maleimide  
Cyanine3 NHS ester    1032678-38-8
Cyanine3.5 azide  
Cyanine3.5 carboxylic acid 1144107-79-8
Cyanine3.5 NHS ester  
Cyanine5 alkyne  
Cyanine5 amine  
Cyanine5 azide  
Cyanine5 Boc-hydrazide  
Cyanine5 carboxylic acid  
Cyanine5 DBCO  
Cyanine5 hydrazide  
Cyanine5 maleimide  
Cyanine5 NHS ester    1032678-42-4
Cyanine5.5 alkyne  
Cyanine5.5 amine  
Cyanine5.5 azide  
Cyanine5.5 carboxylic acid 1144107-80-1
Cyanine5.5 hydrazide  
Cyanine5.5 maleimide  
Cyanine5.5 NHS ester  
Cyanine7 alkyne  
Cyanine7 amine        1650635-41-8
Cyanine7 azide  
Cyanine7 carboxylic acid  
Cyanine7 DBCO  
Cyanine7 dicarboxylic acid  
Cyanine7 hydrazide  
Cyanine7 maleimide  
Cyanine7 NHS ester  
Cyanine7.5 alkyne  
Cyanine7.5 amine  
Cyanine7.5 azide  
Cyanine7.5 carboxylic acid 16147-68-1
Cyanine7.5 hydrazide  
Cyanine7.5 maleimide  
Cyanine7.5 NHS ester  
DBCO-Acid             1353016-70-2
DBCO-Amine            1255942-06-3
DBCO-C6-Acid          1425485-72-8
DBCO-C6-NHS Ester     1384870-47-6
DBCO-Maleimide        13957-30-7
Sulfo DBCO-PEG4-Amine 1416711-60-8
DBCO-PEG13-NHS Ester  
DBCO-PEG4-Biotin      1255942-07-4
DBCO-PEG4-DBCO  
DBCO-PEG4-Desthiobiotin  
DBCO-PEG4-Maleimide   1480516-75-3
DBCO-PEG4-NHS Ester   1427004-19-0
DBCO-PEG5-Acid  
DBCO-PEG5-NHS Ester   1378531-80-6
DBCO-Sulfo-NHS Ester  1400191-52-7
Dde Biotin Picolyl Azide  
Dde Biotin-Alkyne  
Dde Biotin-Azide  
Dde Biotin-DBCO  
Desthiobiotin-PEG3-Azide 1306615-47-3
Desthiobiotin-PEG4-Alkyne  
Diacetate-5-FAM-NHS   150206-05-6
Diacetate-6-FAM-NHS   150206-15-8
Diazo Biotin-Alkyne  
Diazo Biotin-Azide    1339202-33-3
Diazo Biotin-DBCO  
Diol Biotin-Alkyne  
Diol Biotin-Azide  
Dipiv-5-FAM  
Dipiv-5-FAM-Osu (NHS)  
Disulfide Biotin Azide  
DTPABMA 119895-95-3
FAM alkyne, 5-isomer  510758-19-7
FAM alkyne, 6-isomer  478801-49-9
FAM amine, 5-isomer  
FAM amine, 6-isomer  
FAM azide, 5-isomer  
FAM azide, 6-isomer   13385-76-7
FAM hydrazide, 5-isomer  
FAM maleimide, 6-isomer  
FAM NHS ester, 6-isomer  
FAM Picolyl Azide  
Fluorescein-Biotin-Azide  
Fmoc-N-amido-PEG6-acid 882847-34-9
Fmoc-NH-PEG12-CH2CH2COOH 756526-01-9
Fmoc-NH-PEG2-CH2COOH 166108-71-0
Hexadecanoic acid, 1-(aminomethyl)-1,2-ethanediyl ester, hydrochloride 139984-35-3
Hydroxy-PEG3-t-butyl ester 1020-66-6
Hydroxy-PEG6-acid      1347750-85-9
INDEX NAME NOT YET ASSIGNED 18979-61-8
Mal-PEG4-acid          518044-41-2
Mal-PEG4-NHS ester 1325208-25-0
Mal-PEG4-t-butyl ester 518044-36-5
MB 488 DBCO  
MB 488 Picolyl Azide  
MB 532 DBCO  
MB 532 Picolyl Azide  
MB 543 Azide  
MB 543 DBCO  
MB 543 Picolyl Azide  
EdU(5-ethynyl-2'-deoxyuridine) 61135-33-9
DBCO-NHS 1353016-71-3
DBCO-PEG4-Amine       1255942-08-5
   
MB 594 Azide  
MB 594 DBCO  
MB 594 Picolyl Azide  
Methyltetrazine-Acid  1380500-88-8
Methyltetrazine-Amine 1345955-28-3
Methyltetrazine-DBCO  
Methyltetrazine-mPEG, 10 kDa  
Methyltetrazine-mPEG, 20 kDa  
Methyltetrazine-mPEG, 30 kDa  
Methyltetrazine-mPEG, 5 kDa  
Methyltetrazine-NHS Ester 1644644-96-1
Methyltetrazine-PEG12-DBCO  
Methyltetrazine-PEG4-Acid 1807-91-0
Methyltetrazine-PEG4-Alkyne  
Methyltetrazine-PEG4-Amine 1808-05-9
Methyltetrazine-PEG4-Azide  
Methyltetrazine-PEG4-Maleimide 1808-02-6
Methyltetrazine-PEG4-NHS Ester 1807-92-1
Methyltetrazine-PEG4-Sulfo-NHS Ester  
Methyltetrazine-PEG5-NHS Ester  
Methyltetrazine-Propylamine  
Methyltetrazine-Sulfo-NHS Ester  
N-Boc-PEG4-alcohol    106984-09-2
PC Alkyne-NHS Ester  
PC Azido-NHS Ester  
PC Biotin-Alkyne  
PC Biotin-Azide  
PC DBCO-Biotin  
PC DBCO-NHS Ester  
PC Methyltetrazine-NHS Ester  
Pentynoic acid STP ester  
PEP azide  
Perylene azide  
Propargyl-Maleimide    209395-32-4
Propargyl-NHS Ester    1174157-65-3
Pyrene azide 1  
Pyrene azide 2  
Pyrene azide 3  
Pyrene hydrazide  
Pyrene maleimide       42189-56-0
Pyrenebutyric acid     3443-45-6
Pyrenebutyric acid NHS ester 114932-60-4
R110 azide, 5- isomer  
R110 azide, 6- isomer  
R6G azide, 5-isomer  
ROX alkyne, 5-isomer  
ROX azide, 5- isomer  
ROX NHS ester, pure 6- isomer 117491-83-5
S-Acetyl-PEG3-azide    1310827-26-9
S-acetyl-PEG4-alcohol  223611-42-5
S-acetyl-PEG4-amine    1404111-71-2
S-acetyl-PEG4-t-boc-N-amido 1404111-70-1
S-acetyl-PEG4-t-butyl ester 1818294-26-6
S-acetyl-PEG4-Thiol  
S-acetyl-PEG5-alcohol  1000415-61-1
Sulfo DBCO-Amine  
Sulfo DBCO-Maleimide  
Sulfo DBCO-NHS Ester  
Sulfo DBCO-PEG4-Maleimide  
Sulfo-Cyanine3 alkyne  10103-62-5
Sulfo-Cyanine3 amine  
Sulfo-Cyanine3 azide  
Sulfo-Cyanine3 carboxylic acid  
Sulfo-Cyanine3 maleimide  
Sulfo-Cyanine3 NHS ester 146368-16-3
Sulfo-Cyanine3 tetrazine  
Sulfo-Cyanine5 alkyne  
Sulfo-Cyanine5 amine  
Sulfo-Cyanine5 azide  
Sulfo-Cyanine5 bis-NHS ester  
Sulfo-Cyanine5 carboxylic acid 1121756-16-8
Sulfo-Cyanine5 maleimide  
Sulfo-Cyanine5 NHS ester  
Sulfo-Cyanine5 tetrazine  
Sulfo-Cyanine5.5 alkyne  
Sulfo-Cyanine5.5 amine  
Sulfo-Cyanine5.5 azide  
Sulfo-Cyanine5.5 carboxylic acid  
Sulfo-Cyanine5.5 maleimide  
Sulfo-Cyanine5.5 NHS ester  
Sulfo-Cyanine7 alkyne  
Sulfo-Cyanine7 amine  
Sulfo-Cyanine7 azide  
Sulfo-Cyanine7 carboxylic acid  
sulfo-Cyanine7 dicarboxylic acid  
Sulfo-Cyanine7 maleimide  
Sulfo-Cyanine7 NHS ester  
sulfo-Cyanine7.5 alkyne  
sulfo-Cyanine7.5 azide  
Sulfo-Cyanine7.5 carboxylic acid  
sulfo-Cyanine7.5 NHS ester  
TAMRA Alkyne  
TAMRA alkyne, 5-isomer 2095193-65-8
TAMRA alkyne, 6-isomer  
TAMRA amine, 5-isomer  
TAMRA Azide 70281-37-7
TAMRA azide, 5-isomer 825651-66-9
TAMRA DBCO  
TAMRA Methyltetrazine  
TAMRA Picolyl Azide  
TAMRA Tetrazine  
TAMRA-Azide-Desthiobiotin  
TAMRA-Biotin-Azide  
t-Boc-N-amido-PEG3-thiol 1895922-68-5
t-Boc-N-amido-PEG4-acid 756525-91-4
TCO-Amine HCl Salt      1609659-02-0
TCO-PEG12-DBCO  
TCO-PEG12-NHS Ester  
TCO-PEG3-Amine  
TCO-PEG3-Maleimide      1609659-01-9
TCO-PEG4-Acid           1813-21-8
TCO-PEG4-NHS Ester      1621096-79-4
TCO-PNB Ester           1438415-89-4
Tetrazine-Acid          1380500-92-4
Tetrazine-Amine         1092689-33-2
Tetrazine-NHS Ester  
Tetrazine-PEG5-NHS Ester 1682653-80-0
Tetrazine-Sulfo-NHS Ester  
ThioLinker-Azide  
ThioLinker-DBCO  
ThioLinker-Tetrazine  
Thiol-PEG2-alcohol      17643-17-3
Thiol-PEG3-acid         1347750-82-6
Thiol-PEG4-alcohol      90952-27-5
Thiol-PEG4-amine        1189760-69-7
Thiol-PEG4-t-butyl ester 564476-33-1
Thiol-PEG5-alcohol      248582-03-8
Thiol-PEG5-azido  
Thiol-PEG8-alcohol      791620-96-7
WS DBCO-Biotin          3444-70-5
WS PC DBCO-Biotin  
[Ru(bpm)3]Cl2           65034-88-0
Ir(dFppy)3              391665-84-2
Ir(dmppy)2(dtbbpy)PF6  1607469-49-7
Ir(dtbppy)2(dtbbpy)PF6 808142-80-5
Ir(p-F-ppy)3  
Ir(piq)3               435293-93-9
Ir(p-MeO-ppy)3         693225-17-1
Ir(ppy)2(bpy)BF4       1359859-65-6
Ir(ppy)2(dtbbpy)PF6    676525-77-2
Ir(ppy)3 94928--6
Ir[(Me)-ppy]3          799241-63-7
Ir[dF(CF3)ppy]2(bpy)PF6 1092775-62-6
Ir[dF(CF3)ppy]2(dtbbpy)PF6 870987-63-6
Ir[dF(Me)ppy]2(dtbbpy)PF6 1335047-34-1
Ir[dF(t-Bu)-ppy]3      1024594-54-4
Ir[dFppy]2(dtbbpy)PF6  1072067-44-7
Ir[p-CF3(Me)-ppy]3  
Ir[p-CF3(t-Bu)-ppy]3  
Ir[p-F(Me)ppy]2(dtbbpy)PF6 808142-88-3
Ir[p-F(t-Bu)-ppy]3     13113-93-2
Ir[p-Me(Me)-ppy]3      851775-39-8
Ru(bpm)3(PF6)2         85335-55-3
Ru(bpy)2(phen-5-NH2)(PF6)2 84537--0
Ru(bpy)3(BF4)2         63950-81-2
Ru(bpy)3(Cl)2          14323-06-9
Ru(bpy)3(Cl)2·6H2O    50525-27-4
Ru(bpy)3(PF6)2         60804-74-2
Ru(bpz)3(Cl)2          80925-50-4
Ru(bpz)3(PF6)2         80907-56-8
Ru(phen)(bpy)2(PF6)2   60828-38-8
Ru(phen)3(PF6)2        60804-75-3
Ru(ppy)3(PF6)2         1189516-45-7
t-Boc-N-Amido-PEG3-amine 101187-40-0
TCO-NHS Ester          1191901-33-3
Trans-Cyclooct-4-en-1-ol 4277-34-3