The English Introduction

Bis-sulfone NHS Ester is a unique heterobifunctional building block with amine and sulfhydryl/thiol reactivity that overcomes the drawbacks associated with the use of traditional sulfhydryl labeling chemistry. Traditional sulfhydryl labeling chemistry cleaves disulfide bridges and leaves them in “open form”, which may compromise the stability and function of an antibody or other proteins. Bis-sulfone reagents re-bridge the disulfide bond, and enhance the structural stability of the protein.

Molecular weight	597.66
Chemical composition	C29H27NO9S2
CAS	899452-51-8
Solubility	DMSO, DMF, DCM, THF, Chloroform
Purity	>95% (HPLC)
Appearance	White crystalline
Storage conditions	-20C
Shipping conditions	Ambient temperature

Click Chemistry Tool

DBCO Reagents

Amine Reactive

DBCO-C6-NHS Ester

• DBCO-NHS Ester
• DBCO-Sulfo-NHS Ester
• DBCO-PEG4-NHS Ester
• DBCO-PEG5-NHS Ester
• DBCO-PEG13-NHS Ester
• PC DBCO-NHS Ester
• DBCO-C6-Acid
• DBCO-Acid
• DBCO-PEG5-Acid

Carboxyl/Carbonyl Reactive

• DBCO-Amine
• DBCO-PEG4-Amine
• Sulfo DBCO-PEG4-Amine
• Sulfo DBCO-Amine

 Sulfhydryl Reactive

• Sulfo DBCO-Maleimide

DBCO-Maleimide

• Sulfo DBCO-PEG4-Maleimide
• DBCO-PEG4-Maleimide
• Bis-sulfone-PEG4-DBCO
• ThioLinker-DBCO

Fluorescent Probes

• MB 532 DBCO

MB 488 DBCO

• MB 543 DBCO
• MB 594 DBCO
• Carboxyrhodamine 110 DBCO
• TAMRA DBCO
• Cy3 DBCO
• Cy5 DBCO
• Cy5.5 DBCO
• Cy7 DBCO

 Biotinylation Reagents

• DBCO-PEG4-Biotin

WS DBCO-Biotin

• DBCO-PEG4-Desthiobiotin
• Dde Biotin-DBCO
• PC DBCO-Biotin
• WS PC DBCO-Biotin
• Diazo Biotin-DBCO

PEGylation Reagents

• DBCO-mPEG, 5 kDa

DBCO-mPEG, 10 kDa

• DBCO-mPEG, 20 kDa
• DBCO-mPEG, 30 kDa

 Bifunctional Crosslinkers

• Methyltetrazine-DBCO

Methyltetrazine-PEG12-DBCO

• DBCO-PEG4-DBCO
• TCO-PEG12-DBCO

 Miscellaneous Reagents

• DBCO-PEG4-Hydroxyl

中文介绍

Bis-sulfone NHS Ester，硫醇反应性克服了传统巯基标记化学的缺点。传统的巯基标记化学方法会将二硫醚桥接在一起，使桥接体保持开放状态，这可能会影响抗体或其他蛋白质的稳定性和功能。Bis-sulfone试剂重新桥接二硫键，增强蛋白质的结构稳定性。

分子量	597.66
分子式	C29H27NO9S2
CAS	899452-51-8
溶解度	DMSO, DMF, DCM, THF, Chloroform
含量	>95% (HPLC)
外观	白色透明晶体
储存	-20C
运输	环境温度

西安凯新生物科技有限公司是国内的功能化PEG修饰纳米金及纳米金棒的供应商，我们可以提供多达十几种的活性基团及各种不同的蛋白分子或聚合物。我公司能和PEG通过双硫键偶连的Gold Nanorods的LSPR从600nm-1000nm不等，我们偶连的PEG末端带有功能活性基团可以和NH2，MAL，COOH，SH，NHS活化连接不同的蛋白或分子。

 

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