L-Homopropargylglycine,HPG,炔标记蛋氨酸

L-Homopropargylglycine,HPG,炔标记蛋氨酸

L-Homopropargylglycine

L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety that can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or &lduo;click &rduo; reaction between an azide and an alkyne or cyclooctyne. The alkyne-modified protein is detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and patible with downstream LC-MS⁄MS and MALDI MS analysis.

L-Homopropargylglycine,HPG,炔标记蛋氨酸

公司：西安凯新生物科技有限公司

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