7424-00-2-4-氯-DL-苯丙氨酸 Sigma-上海联硕生物科技有限公司

参考价	面议

产品简介

CAS号	7424-00-2	产地	进口
规格	5g	级别	食品级

名称：4-氯-DL-苯丙氨酸 Sigma
描述：4-氯-DL-苯丙氨酸（PCPA）是5-羟色胺（5-HT）合成的抑制剂。有助于改善肺组织炎症，重塑肺动脉。PCPA可降低色氨酸羟化酶1（TPH1）、基质金属蛋白酶（MMP）和促炎因子的表达色氨酸羟化酶抑制剂。

详细介绍

4-氯-DL-苯丙氨酸 Sigma

Application

4-Chloro-DL-phenylalanine has been used:
• as tryptophan hydroxylase 1 (TPH1) inhibitor to treat kras⁺ male zebrafish^[2]
• to induce insomnia in rat models^[3]
• used to treat embryos to examine its effect on serotonin^[4]
• for the selection of Enterococcus faecalis transformants with pESentA32 plasmid^[5]
• to feed flies to explore serotonin effect^[6]

包装

5, 25 g in poly bottle

Features and Benefits

该化合物也是Sigma药理活性化合物库（LOPAC^®¹²⁸⁰）的一部分，该化合物库是一个具有生物学注释的高品质、可即时筛选化合物的集合。

性质

Related Categories	Chemical Synthesis, Enzyme Inhibitors, Greener Alternative Products, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Re−engineered Products, Tryptophan Hydroxylase, 细胞信号转导和神经科学, 细胞生物学 Less...
Quality Level	100
greener alternative product characteristics	Waste Prevention Designing Safer Chemicals Reduce Derivatives Learn more about the Principles of Green Chemistry.
mp	>240 °C (dec.) (lit.)
greener alternative category	Re-engineered
storage temp.	room temp
SMILES string	NC(Cc1ccc(Cl)cc1)C(O)=O
InChI	1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChI key	NIGWMJHCCYYCSF-UHFFFAOYSA-N
Gene Information	human ... TPH1(7166), TPH2(121278)