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详细介绍
二苯并环辛烯PEG羧基 ，DBCO-PEG-COOH，产品芃硕生物专业供应。
名称 | 货号 | 英文名、缩写 | 分子量 | 规格 |
DBCO-PEG-COOH | PS2-CMDB-5K | DBCO-PEG-COOH | 5000 | 0.1g、0.5g |
DBCO-PEG-COOH | PS2-CMDB-2K | DBCO-PEG-COOH | 2000 | 0.1g、0.5g |
DBCO-PEG-COOH | PS2-CMDB-3K | DBCO-PEG-COOH | 3400 | 0.1g、0.5g |
DBCO-PEG-COOH | PS2-CMDB-1K | DBCO-PEG-COOH | 1000 | 0.1g、0.5g |
DBCO-PEG-COOH | PS2-CMDB-10K | DBCO-PEG-COOH | 10000 | 0.1g、0.5g |
（备注：非常规分子量：400、600。精确聚合度的小分子定制。）
结构式：
基本信息：
中文名称：二苯并环辛烯-聚乙二醇-羧基 (DBCO-PEG-COOH)
别名：DBCO-PEG-COOH
英文名称：DBCO-PEG-COOH，DBCO-PEG-ACID
CAS：-
分子量：400、600、1K、2K、3.4K、4K、5K、10K
纯度：95%以上
二苯并环辛烯PEG羧基 ，DBCO-PEG-COOH，产品芃硕生物专业供应。
应用简介：
Ponsure’DBCO (dibenzocyclooctyne) PEG acid, DBCO-PEG-COOH, is a heterobifunctional reactive PEG derivative that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneously without the need for toxic Cu catalysts. Carboxylic acid group, on the other hand, can be activated to react with amines, hydroxy and other functional groups.
Copper-free Click reaction procedures:
Prepare the azide-containing reagents in reaction buffer.
Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4℃.
Purify conjugates either by dialysis or size-exclusion chromatograph.
物理性质：
状态：淡黄色到白色固体，或者半固体，取决于分子量。
溶解性：溶于水，DMSO等溶剂。
保持条件：-20℃*保存，避光，干燥。
注意事项：取用一定要干燥，避免频繁的溶解和冻干。
反应性：DBCO与含有N3基团的反应。COOH可以和NH2、OH等反应。
二苯并环辛烯PEG羧基 ，DBCO-PEG-COOH，产品芃硕生物专业供应。
技术指标：
纯度（PEG）：95%以上
取代率（DBCO）：90%以上
取代率（COOH）：95%以上
分散系数（PDI）：小于等于1.05
分析：COA、GPC、NMR、MALDI-TOF
相关产品*：
MPEG-COOH
HOOC-PEG-COOH
4ARM-PEG-COOH
6ARM-PEG-COOH
8ARM-PEG-COOH
HO-PEG-COOH
BOC-NH-PEG-COOH
FMOC-NH-PEG-COOH
NH2-PEG-COOH
DSPE-PEG-COOH
DPPE-PEG-COOH
DMPE-PEG-COOH
DOPE-PEG-COOH
HOOC-PEG-T-butyl acetate
HS-PEG-COOH
OPSS-PEG-COOH
DA-PEG-COOH(ACRL-PEG-COOH)
ACA-PEG-COOH
ALKYNE-PEG-COOH
N3-PEG-COOH
MAL-PEG-COOH
LA-PEG-COOH
BIOTIN-PEG-COOH
SILANE-PEG-COOH
Cholesterol-PEG-COOH
FA-PEG-COOH
FITC-PEG-COOH
RB-PEG-COOH
CY5-PEG-COOH
DBCO-PEG-COOH
PLA-PEG-COOH
PCL-PEG-COOH
PLGA-PEG-COOH
Furan-PEG-COOH
Pyrene-PEG-COOH
二苯并环辛烯PEG羧基 ，DBCO-PEG-COOH，产品芃硕生物专业供应。
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