羧甲基-β-环糊精

CAS号： 10016-20-3

分子式： C36H60O30

英文名称： Alfadex

英文同义词： alpha-Cyclodextrin; alpha-cycloamylose; alpha-dextrin; Cyclohexaamylose hydrate; cyclomaltohexose; （1S,3R,6S,8R,11S,13R,16S,18R,21S,23R,26S,28R）-5,10,15,20,25,30-hexakis（hydroxymethyl）-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol （non-preferred name）; 5,10,15,20,25,30-hexakis（hydroxymethyl）-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol （non-preferred name）; （1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R）-5,10,15,20,25,30-hexakis（hydroxymethyl）-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.2~3,6~.2~8,11~.2~13,16~.2~18,21~.2~23,26~]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol （non-preferred name）

EINECS号： 233-007-4

分子量： 972.8436

沸点： 1410.846°C at 760 mmHg

密度： 0mmHg at 25°C

闪点： 807.051°C

简介：羧甲基 -β- 环糊精在PH较低的溶液中溶解度低，但在中、碱性溶液（ PH>4 ）中，由于羧基解离，可以任意浓度溶解，而且其结构疏松，自流动性明显改善。在人体肠道 PH 6-7 的环境中具有很好的溶解性，可在药物延长释放剂型中使用，同时具有比 HP-β-CD 更低的溶血