地诺前列素氨丁三醇 Dinoprost Trometamol

Dinoprost(Prostaglandin F2_alpha_)氨基丁三醇盐是一前列腺素。

Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
In domestic mammals, it is produced by the uterus when stimulated by oxytocin, in the event that there has been no implantation during the follicular phase. It acts on the corpus luteum to cause luteolysis, forming a corpus albicans and stopping the production of progesterone. Action of PGF2α is dependent on the number of receptors on the corpus luteum membrane.
The PGF2α isoform 8-iso-PGF2α was found in significantly increased amounts in patients with endometriosis, thus being a potential causative link in endometriosis-associated oxidative stress.

中文别名:

地诺前列腺素 氨丁三醇;

前列腺素 F2ΑTRIS 盐

 英文别名:

panacelan f tromethamine salt;

prosta-5, 9,11,15-trihydroxy-, (5z,9.alpha.,11.alpha.,13e,15s)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)